Medicinal chemistry

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    Microbial iron scavengers

    1 January 2009

    Medicinal and analytical chemists take their cue from micro-organisms' ability to bind to iron in the design of new drugs and sensors

  • The dendrimer-based active ingredient (blue and red) in Starpharma's anti-HIV agent VivaGel binds to specific receptors (yellow) on the surface of HIV, preventing fusion with human cells

    Nanomedicine arrives

    1 July 2008

    Nanoscale chemical entities target the building blocks of biology with medicinal consequences

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    Phenols in medicine

    1 January 2007

    Phenol encountered in school or college chemistry laboratories demands special respect on account of its toxic and corrosive nature. But phenol and its derivatives do have a few medicinal surprises

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    Spicing up Chemistry

    1 May 2006

    Spices have been used in cooking since Roman times, and were believed to be important as antiparasitic agents and as gastrointestinal protectants in the diet

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    Chemistry, medicine and genetic analysis

    1 March 2006

    In the near future, doctors will be able to carry out a 'while you wait' test, using genetic analysis, for chlamydia, the silent disease that can lead to infertility in women.

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    Pain relief: from coal tar to paracetamol

    1 July 2005

    Analgesics, ie pain-relieving drugs, fall into two categories: those that also reduce body temperature in fevers (antipyretics), and those that act mainly on the brain - typically morphine and diamorphine/heroin. Here we consider members of the first group, particularly those once designated 'coal tar analgesics'. Paracetamol, our most popular over-the-counter ...